Iron, found in many OTC multivitamins, prenatal vitamins, and supplements, can cause intoxication if ingested by an animal. Of note, iron can also be found in fertilizers, pesticides, single use hand warmers and heating pads such as ThermaCare.

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Signs and symptoms of toxicity: Clinical signs of poisoning include vomiting, bloody diarrhea, fatigue, abdominal pain, low blood pressure, rapid heart beat, tremors, seizures, and coma.

Toxic consumption: Toxicity in dogs can be seen at doses greater than 20 mg/kg (9 mg/lb) of elemental iron. It is very important to determine the amount of elemental iron in the product. This information may be found on the label. There is no established threshold for toxicity in cats and all incidents of accidental consumption should be reported.

Dogs: Elemental Iron Toxic Consumption
X-Small
Yorkie, Chihuahua
Small
Pug, Boston Terrier, Poodle
Medium
Beagle, Scottish Terrier
Large
Boxer, Cocker Spaniel
X-Large
Retriever, German Shepherd
XX-Large
Great Dane, St. Bernard
1 – 10 lbs.
(0.45 – 4.6 kg)
11 – 25 lbs.
(5 – 11.4 kg)
26 – 40 lbs.
(11.8 – 18.2 kg)
41 – 70 lbs.
(18.6 – 31.8 kg)
71 – 90 lbs.
(32.3 – 40.9 kg)
91 – 110 lbs.
(41.4 – 50 kg)
dog1 dog2 dog3 dog4 dog7 dog6
> 9 mg > 100 mg > 236 mg > 372 mg > 646 mg > 828 mg

 

References:
Albertson, J. (2006). The toxicity of iron, an essential element. Veterinary medicine (February).